Override for Setup.exe and %cache% file questions

Hello, we see this file at a site or two, on all workstations, possibly related to some program updates.
1.) How can we identify these and trust/allow or deny?
 
SETUP.EXE    
%programfiles%installshield installation information{4b9f9f02-1396-4396-9fcc-ccbeecb276f8}
1.1 MB    
Jul 30th 2015, 06:01
99 day 14 hr 6 min 51 sec
 
SETUP.EXE
%programfiles%installshield installation information{a1db461c-2907-4373-ada0-ccc23bb717b4}
1.1 MB
Jul 31st 2015, 08:01
100 day 16 hr 7 min 52 sec
 
2.) %cache% files

20120806-002-I32[1].EXE    
%cache%    
41.0 MB    
Jul 29th 2015, 06:51    
7 day 18 min 16 sec

20120806-002-I32[2].EXE
%cache%
37.9 MB
Jul 29th 2015, 06:51    
7 day 18 min 16 sec